You can make updates to the content and layout of the pages in your design as many times as needed, as long as the issue is unpublished.
Selecting the Open Design button from the Manage Publication page will open TigerDesigner and load the pages and panels of your design. You are then ready to edit the content of your pages (You can also work on any interactive elements but selecting the Interactivity tab). Bear in mind that TigerDesigner will auto-save your changes and these cannot be undone.
When you exit designer, if you have made changes you will be prompted to update your issue.
You can also update your issue by selecting the blue Export arrow from the left-hand menu. You will be presented with two options:
Overwrite the current design with the updated version.
Update Issue (Advanced)
As above but with additional options, such as 'simplify issue' which produces the issue in a simpler format.
Your design can also be exported to the latest version from the homepage - simply select the refresh icon on the issue thumbnail image.